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Growth stimulation: Anabolic steroids were used heavily by pediatric endocrinologists for children with growth failure from the 1960s through the 1980s. These steroid hormones effectively stimulate growth of the children's body tissues and organs, and stimulate body weight management. The children also received low doses of growth-promoting drugs such as growth hormone and glucocorticoids for their growth and growth in later years. Prolonged steroid usage: Since the 1950s, many growth stimulation agents (e.g., glucocorticoids) have been utilized and used indefinitely, including steroid abuse by children. Although steroids have numerous side effects, such as depression, increased aggression, premature aging of the body, low immunity, and increased hair growth, the abuse of steroids is a cause of increased morbidity, mortality, and economic loss among people younger than 40 years old.1,6 Drug addiction: The drug addiction treatment for steroid abuse includes behavioral, psychiatric, and surgical treatments. A person can develop tolerance to the effect of steroids, leading to compulsive steroid use over months or even years, potentially resulting in severe steroid abuse and dependence. Other side effects and negative medical effects of steroid treatment include depression, impaired thinking and speech, gastrointestinal upset, anorexia, and constipation, according to the American Association of Psychiatry and Neurology.1 Effects on the Endocrine System The effect of steroid abuse on the endocrine system of the body may result directly or indirectly from steroid abuse and a variety of other pharmacological and nonpharmacological effects. Some of the adverse effects of steroid abuse include: Decreased levels of the testosterone hormone in the blood, sometimes referred to as hypogonadism. Decreased levels of insulin, the blood-sugar regulator, resulting in delayed hypoglycemia. Decreased levels of the progesterone hormone, a hormone responsible for egg maturation, which can lead to delayed ovulation, diminished fertility, and premature menopause. Infertility, or lack of a pregnancy. Decreased serum testosterone, often in response to steroid abuse. Decreased estrogen, which may lead to anemia. Increased hair growth, especially in a woman. Loss of body fat, often because of muscle loss. Increased body temperature, such as when taking a cold bath or shower. Pregnancy complications, such as premature rupture of membranes (PPO). Hemorrhaging of the endocrine system (hemorrhagic shock). Changes in hair growth, including receding hair, thinning Related Article:

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